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Artane alters unusual nerve impulses and relaxes stiff muscles.

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INSTRUCTIONS

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Take trihexyphenidyl exactly as directed through your doctor. If you do not understand these directions, ask the pharmacist, nurse, or doctor to spell out them to you.
Take each dose having a full glass of water. Trihexyphenidyl might be taken with or without meals. Taking trihexyphenidyl with food may lessen stomach upset.

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Before taking trihexyphenidyl, tell your doctor or pharmacist if you are allergic to it; or if you might have every other allergies. This product may contain inactive ingredients, which may cause hypersensitive reactions and other problems. Talk to your friendly phamacist for more details.

This medication shouldn't be used if you have certain health conditions. Before using this medicine, confer with your doctor or pharmacist if you might have: certain eye problem (narrow-angle glaucoma), blockage in the bladder/esophagus/stomach/intestines (e.g., bowel obstruction), severe ulcerative colitis.

Before applying this medication, inform your doctor or pharmacist your medical history, especially of: alcohol use, breathing problems (e.g., asthma, emphysema), diarrhea a result of contamination, certain eye problem.

To give you an accurate dose, measure the liquid type of trihexyphenidyl which has a special dose-measuring spoon or cup, not which has a regular table spoon.

If you miss a dose take the missed dose once you remember. However, if it is almost time for the next dose, skip the missed dose in support of go ahead and take next regularly scheduled dose. Do not take a double dose of this medication.

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DOSAGE 

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Dosage needs to be individualized. The initial dose needs to be low and then increased gradually, particularly in patients over 60 years old. Whether ARTANE (trihexyphenidyl HCl) may best be given before or after meals needs to be driven by what sort of patient reacts. Postencephalitic patients, who're usually prone to excessive salivation, may want to take it after meals and may, moreover, require small amounts of atropine which, under such circumstances, may also be an efficient adjuvant. If ARTANE (trihexyphenidyl) has a tendency to dry the mouth excessively, it could possibly be easier to go on it before meals, unless it causes nausea. If taken after meals, the thirst sometimes induced can be allayed by mint candies, nicotine gum or water.

Abrupt withdrawal for the treatment of parkinsonism may result in acute exacerbation of parkinsonism symptoms; therefore, abrupt withdrawal should be avoided.

Abrupt withdrawal of treatment may result in neuroleptic malignant syndrome (NMS).

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STORAGE

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Store Artane at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store faraway from heat, moisture, and light. Do not store within the bathroom. Keep in a strong, light-resistant container. Keep Artane out from the reach of children and faraway from pets.

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Dosage needs to be individualized. The initial dose needs to be low and then increased gradually, particularly in patients over 60 years old. Whether ARTANE (trihexyphenidyl HCl) may best receive before or after meals needs to be driven by the way the patient reacts. Postencephalitic patients, that are usually more prone to excessive salivation, may choose to get it after meals and could, furthermore, require small amounts of atropine which, under such circumstances, might be a highly effective adjuvant. If ARTANE (trihexyphenidyl) is likely to dry the mouth excessively, it may be safer to go on it before meals, unless it causes nausea. If taken after meals, the thirst sometimes induced can be allayed by mint candies, gum or water.

Abrupt withdrawal for the treatment of parkinsonism may result in acute exacerbation of parkinsonism symptoms; therefore, abrupt withdrawal must be avoided.

Abrupt withdrawal of treatment may result in neuroleptic malignant syndrome (NMS).

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Store Artane at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and lightweight. Do not store inside the bathroom. Keep in a tight, light-resistant container. Keep Artane out from the reach of children and from pets.

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Side Effects

Minor side effects, including dryness from the mouth, blurred vision, dizziness, mild nausea or nervousness, will probably be seen by 30 to 50 percent of patients. These sensations, however, less complicated less troublesome with ARTANE (trihexyphenidyl) than with belladonna alkaloids and they are usually less disturbing than unallenated parkinsonism. Such reactions usually become less pronounced, and even to completely disappear, as treatment continues. Even before these reactions have remitted spontaneously, they may often be controlled by careful adjustment of dosage form, level of drug, or interval between doses.

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If you experience any of the following serious side effects, stop taking trihexyphenidyl and seek emergency medical help or contact your doctor immediately:

Other, less serious negative effects might be more likely to occur. Continue to take trihexyphenidyl and confer with your doctor if you experience:

This is not a complete set of negative effects while others may occur. Call your physician for medical advice about side effects.

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Precautions

Patients with cardiac, liver, or kidney disorders, or with hypertension, must be assessed.

Since ARTANE (trihexyphenidyl) has atropine-like properties, patients on long-term treatment must be carefully monitored for untoward reactions.

Since ARTANE (trihexyphenidyl) has parasympatholytic activity, it must be used with caution in patients with glaucoma, obstructive disease in the gastrointestinal or genitourinary tracts, plus elderly males with possible prostatic hypertrophy. Incipient glaucoma could possibly be precipitated by parasympatholytic drugs for example ARTANE (trihexyphenidyl).

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Do not use Artane without first actually talking to a medical expert if you have:

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Before taking this medication, educate doctor if you've:

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You might require a dosage adjustment or special monitoring during treatment if you've any with the conditions listed above.
It is not known whether trihexyphenidyl will probably be unhealthy for an unborn baby. Do not take medicines without first actually talking to your medical professional if you're pregnant or could become pregnant during treatment. It is not known whether trihexyphenidyl passes into breast milk. Do not take this medication without first actually talking to your doctor if you're breast-feeding an infant.

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