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INDICATIONS

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Detrol is indicated for the treatment of overactive bladder with signs and symptoms of urge urinary incontinence, urgency, and frequency.

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INSTRUCTIONS

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Take Detrol exactly as prescribed by your doctor. Do not take in larger or smaller amounts and over recommended. Follow the directions in your prescription label.

Your doctor may occasionally make positive changes to dose to ensure that you get the best results.

Take Detrol with water. Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill might cause a lot of drug to be removed in the past.

Store Detrol at room temperature away from moisture and warmth.

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If you missed a dose - take the missed dose as soon as you remember. Skip the missed dose whether it is almost time for your forthcoming scheduled dose. Do not take extra medicine to generate in the missed dose.

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DOSAGE

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The recommended dose of Detrol Capsules is 4 mg once daily with water and swallowed whole. The dose could be lowered to 2 mg daily based on individual response and tolerability; however, limited efficacy data are available for Detrol 2 mg.

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For patients with mild to moderate hepatic impairment (Child-Pugh Class A or B) or severe renal impairment (CCr 10-30 mL/min), the recommended dose of Detrol is 2 mg once daily. Detrol isn't recommended for utilization in patients with severe hepatic impairment (Child-Pugh Class C). Patients with CCKlO mL/min weren't studied and employ of Detrol on this population is just not recommended.

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For patients who will be taking drugs which might be potent inhibitors of CYP3A4 [e.g., ketoconazole, clarithromycin, ritonavir], the recommended dose of Detrol is 2 mg once daily.

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STORAGE

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Store Detrol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and lightweight. Do not store in the bathroom. Keep Detrol out from the reach of kids and from pets.

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Side Effects

Get emergency medical help for those who have any of these signs and symptoms of a hypersensitive reaction to Detrol: hives; breathlessness; swelling of your face, lips, tongue, or throat. Stop using Detrol and call your doctor at the same time in case you have all of these serious unwanted side effects:

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Less serious Detrol unwanted effects can include:

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This is not a complete report on negative effects among others may occur. Call your physician for health advice about side effects.

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Precautions

Before taking tolterodine, tell your medical professional or pharmacist in case you are allergic for it; or if you have some other allergies. This product might have inactive ingredients, that may cause allergy symptoms or another problems. Talk to your pharmacist for more information.

This medication should not be used in case you have certain medical conditions. Before using this medicine, consult your medical professional or pharmacist if you have: problems emptying your bladder (urinary retention), severe blockage of stomach/intestines (gastric retention), a certain eye condition (uncontrolled narrow-angle glaucoma).

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Before employing this medication, tell a medical expert or pharmacist your track record, especially of: other bladder problems (e.g., bladder outflow obstruction), stomach/intestinal disease (e.g., ulcerative colitis), slowed movement of stomach/intestines, severe constipation, controlled narrow-angle glaucoma, kidney disease, liver disease, enlarged prostate, a specific muscle disease (myasthenia gravis).

Tolterodine could cause a disorder that affects the guts rhythm (QT prolongation). QT prolongation can infrequently bring about serious (rarely fatal) fast/irregular heartbeat along with other symptoms (such as severe dizziness, fainting) that want immediate medical help. The chance of QT prolongation could be increased in case you have certain medical conditions or are taking other drugs which could affect the center rhythm (see also Drug Interactions section). Before using tolterodine, tell your physician or pharmacist if you have any of these conditions: certain heart disease (heart failure, slow heartbeat, QT prolongation inside EKG), genealogy of certain heart related illnesses (QT prolongation inside EKG, sudden cardiac death).

Low numbers of potassium or magnesium inside the blood can also increase your risk of QT prolongation. This risk may increase if you are using certain drugs (like diuretics/"water pills") or if you have conditions like severe sweating, diarrhea, or vomiting. Talk to your medical professional about using tolterodine safely.

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or inflict activity that needs alertness or clear vision until you are sure you'll be able to perform such activities safely. Limit alcohol based drinks.

This medication may cause decreased sweating. Avoid becoming overheated in warm weather, saunas, or during exercise or other strenuous activities since heatstroke may occur.

Kidney function declines when you get older. This medication is slowly removed by the kidneys. Therefore, older people could possibly be more responsive to this drug.

This medication should be used only once clearly needed during pregnancy. It is not known whether Detrol will harm an baby. Tell a medical expert if you are pregnant or want to conceive while employing this medication. Discuss the risks and benefits with your medical professional.

It is unknown if it drug passes into breast milk. Consult your physician before breast-feeding.

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