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Eldepryl is indicated as an adjunct inside control over Parkinsonian patients receiving care with levodopa/carbidopa who exhibit deterioration inside the quality of these a reaction to this therapy.


Take this medicine only as directed through your doctor. Do not take more of it, do not take it more regularly, and do not take it much more time than your doctor ordered.

It is most beneficial to adopt this medicine before breakfast and without liquids.

If you're with all the disintegrating tablet, ensure both hands are dry before you decide to handle the tablet. Do not open the blister pack which contains the tablet until you might be ready to take it. Remove these days from your blister pack by peeling back the foil, then taking today out. Do not push these days over the foil. Do not break or split these days. Place these days on the top of your tongue, where it'll melt quickly. Do not eat food or drink liquids for 5 minutes before or after using this medicine.

If you miss a dose of the medicine, go as soon as possible. However, if it is almost time for your forthcoming dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


The dose with this medicine will change for various patients. Follow your medical professional's orders or even the directions around the label. The following information includes merely the average doses of the medicine. If your dose is different, don't put it back unless a medical expert notifys you to do this.

The amount of medicine that you simply take depends about the strength with the medicine. Also, the number of doses you are taking every day, time allowed between doses, as well as the length of time you're taking the medicine depend for the disease for which you are while using the medicine.
For oral dosage form (tablets):
For Parkinson's disease:


Store the medicine in a very closed container at room temperature, from heat, moisture, and direct light. Keep from freezing.
Keep out from the reach of children.
Do not keep outdated medicine or medicine no longer needed.


Eldepryl is really a levorotatory acetylenic derivative of phenethylamine. It is commonly known within the clinical and pharmacological literature as l-deprenyl.

Side Effects

Along with its needed effects, medicine might cause some unwanted side effects. Although not many of these unwanted side effects may occur, should they do occur they could need medical assistance.

Check with your doctor immediately if any of these negative effects occur:

More common
Chest pain (severe)
enlarged pupils
fast or slow heartbeat
headache (severe)
increase in unusual movements from the body
increased sensitivity from the eyes to light
increased sweating (possibly with fever or cold, clammy skin)
mood or another mental changes
nausea and vomiting (severe)
stiff or sore neck

Less common or rare
Bloody or black, tarry stools
convulsions (seizures)
decreased urine
difficult or frequent urination
difficulty with breathing
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness, particularly if arising from your lying or sitting position
dry mouth
hallucinations (seeing, hearing, or feeling issues that aren't there)
increased thirst
irregular heartbeat
large, flat, blue, or purplish patches within the skin
lip smacking or puckering
loss of appetite
loss of balance control
muscle pain or cramps
nausea or vomiting
numbness or tingling within the hands, feet, or lips
puffing of the cheeks
rapid or worm-like movements from the tongue
restlessness or wish to keep moving
severe stomach pain
shakiness within the legs, arms, hands, or feet
shortness of breath
swelling in the feet or lower legs
swelling or inflammation with the mouth
tightness within the chest
trembling or shaking in the hands or feet
twisting movements from the body
uncontrolled chewing movements
uncontrolled movements from the face, neck, back, arms, or legs
unusual tiredness or weakness
vomiting of blood or material that appears like coffee grounds

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose
Agitation or irritability
chest pain
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low hypertension
severe spasm where the head and heels are bent backward as well as the body arched forward
troubled breathing

Some negative effects may occur that always usually do not need medical attention. These unwanted effects may go away during treatment since your body adjusts on the medicine. Also, your wellbeing care professional may be able to share with you methods to prevent or reduce a few of these unwanted effects. Check together with your health care professional if these things unwanted side effects continue or are bothersome or if you've got any queries about them:

More common
Abdominal or stomach pain
dizziness or feeling faint
runny nose
stuffy nose
trouble with sleeping

Less common or rare
back or leg pain
blurred or double vision
body aches or pain
burning of the lips, mouth, or throat
dryness or soreness from the throat
frequent urge to urinate
inability to move
increased sweating
irritability (temporary)
memory problems
pounding or fast heartbeat
red, raised, or itchy skin
ringing or buzzing within the ears
slow or difficult urination
slowed movements
taste changes
uncontrolled closing in the eyelids
unusual a feeling of well-being
unusual weight loss
voice changes

Other negative effects unlisted might also occur in some patients. If you notice another effects, check together with your doctor.


It is critical that a medical expert look at your progress at regular visits to allow for changes in your dose also to pay attention to any unwanted effects.

Do not take selegiline if you might have used meperidine (e.g., Demerol®) or even an MAO inhibitor (MAOI) (e.g., isocarboxazid, phenelzine, tranylcypromine, Marplan®, Nardil®, or Parnate®) within the past 2 weeks. If you do, you may develop agitation, confusion, restlessness, stomach or intestinal symptoms, sudden high temperature, elevated blood pressure levels, or severe convulsions.

Do not take cough medicines (e.g., dextromethorphan, Robitussin®, Pediacare®) or pain medicines (e.g., methadone, propoxyphene, tramadol, Darvon®, Dolophine®, Ultram®) while you are by using this medicine. Using these medicines together could cause unwanted effects.

Selegiline might cause serious negative effects when used along with some antidepressants. Tell your physician if you might have used amitriptyline, doxepin, fluoxetine, fluvoxamine, nortriptyline, paroxetine, sertraline, Elavil®, Luvox®, Pamelor®, Paxil®, Prozac®, or Zoloft® within the past 14 days.

When selegiline is taken at doses of 10 mg or less per day for that treatments for Parkinson's disease, there are no restrictions on food or beverages you eat or drink. However, the possibility exists that dangerous reactions, including sudden high hypertension, may occur if doses higher than those used by Parkinson's disease are taken with certain foods, beverages, or any other medicines. These foods, beverages, and medicines include:

Also, for around fourteen days once you stop taking this medicine, these food types, beverages, and also other medicines may continue to react with selegiline if it was used doses higher than those usually used for Parkinson's disease.

Check with your doctor or hospital hospital immediately if severe headache, stiff neck, chest pains, fast heartbeat, or nausea and vomiting occur while you happen to be using this medicine. These may be signs of a serious side-effect that should possess a doctor's attention.

Dizziness, lightheadedness, or fainting may occur, specially when you obtain up from your lying or sitting position. Getting up slowly could help. If the problem continues or gets worse, seek advice from your medical professional.

Selegiline might cause dryness from the mouth. For temporary relief, use sugarless candy or gum, melt pieces of ice with your mouth, or use a saliva substitute. However, should your mouth is constantly on the feel dry for over 2 weeks, check with your physician or dentist. Continuing dryness with the mouth may increase the risk of dental disease, including oral cavaties, gum disease, and fungus infections.

It is essential that your physician look at skin for melanoma (tumor) regularly if you have Parkinson's disease.

Do not stop using this medicine without first checking with your physician. Your doctor may want that you reduce gradually the amount you are taking before stopping completely.

Hallucinations may exist in some patients. This is more widespread with elderly patients. If you've got hallucinations, consult a medical expert.

Some individuals who have used this medicine had unusual alterations in their behavior. Talk with your doctor in the event you start having issues with gambling or increased sexual drive while by using this medicine.

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