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Uses

INDICATIONS

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Imuran is used to avoid rejection of an transplanted kidney. It is probably the group of medicines known as immunosuppressive agents. Azathioprine will lower the body's natural immunity in patients who receive transplants to stop rejection from the new kidney. It is also utilized to relieve pain and swelling for patients with rheumatoid arthritis symptoms.

INSTRUCTIONS

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Use this medicine just as directed because of your doctor. Do not take more of it, or a smaller amount of it, than your medical professional ordered. Taking an excessive amount of may increase the chance of unwanted side effects, and taking weak hands is not going to help your problem.

This medicine is sometimes given as well as other medicines. If you are utilizing several medicines together, be sure to realize how to drive them in the daytime. Ask a medical expert to help you plan ways to be sure you take your medicines in the right times.

Do not stop taking this medicine without first checking with a medical expert.

Imuran sometimes causes nausea / vomiting. Taking this medicine after meals or at bed time may lessen stomach upset. Talk to your medical professional if you have questions or continue to have difficulty with feeling sick.

If you miss a dose with this medicine, go on it immediately. However, if it is almost time for your next dose, skip the missed dose and return to your family dosing schedule. Do not double doses.

DOSAGE

The dose with this medicine changes for different patients. Follow a medical expert's orders or even the directions for the label. The following information includes just the average doses on this medicine. If your dose differs, usually do not change it unless your medical professional informs you to do so.

The level of medicine that you simply take depends for the strength in the medicine. Also, the volume of doses you take on a daily basis, enough time allowed between doses, as well as the period of time you take the medicine depend for the disease you simply are utilizing the medicine.
For oral dosage form (tablets):
For kidney transplant rejection:

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For rheumatoid arthritis symptoms: 

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STORAGE 

Store the medicine in a very closed container at room temperature, far from heat, moisture, and direct light. Keep from freezing.
Keep out from the reach of children.
Do not keep outdated medicine or medicine no more needed.
Ask your healthcare professional the way you should get rid of any medicine you tend not to use.

Side Effects

Along having its needed effects, medicines could cause some uncomfortable side effects. Although not all of these unwanted effects may occur, if they occur they could need medical attention.

Check with a medical expert immediately if any of the following negative effects occur:

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More common

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Rare 

Incidence not known

Some side effects may occur very often don't need medical help. These unwanted side effects may go away during treatment since your body adjusts on the medicine. Also, your overall health care professional could possibly tell you about ways to avoid or reduce many of these side effects. Check with your health care professional if any with the following unwanted effects continue or are bothersome or for those who have any queries about them:
More common
Nausea or vomiting (mild)
swollen joints
Incidence unfamiliar
Hair loss or thinning in the hair

Other side effects unlisted might also occur in some patients. If you notice any other effects, check along with your health care professional.

Call a medical expert for medical advice about negative effects.

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Precautions

If you'll be using this medicine for a long time, it is crucial that your medical professional check you at regular visits for virtually any problems or unwanted effects that may be brought on by this medicine. Blood tests may be needed to evaluate for unwanted side effects.

Using this medicine while you are pregnant may damage your baby. Use an effective kind of birth control to maintain from conceiving. If you think you've got become pregnant while using this medicine, tell your medical professional right away.

Do not use this medicine if you are also taking mercaptopurine (Purinethol®). Using these medicines together might cause serious negative effects.

If you are choosing azathioprine for arthritis, ensure your medical professional knows in case you received chlorambucil (Leukeran®), cyclophosphamide (Cytoxan®, Neosar®), or melphalan (Alkeran®) to help remedy your arthritis within the past. Using azathioprine after these medicines may enhance your risk for unwanted effects. Talk to your medical professional when you have questions regarding this.

This medicine may enhance your likelihood of getting certain types of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). Talk to your physician if you have concerns about it risk.

Use sunscreen or sunblock lotions using a sun protection factor (SPF) with a minimum of 15 regularly when you're outdoors. Wear protective clothing and hats, and remain beyond sunlight between the hours of 10 a.m. and 3 p.m. Avoid sunlamps and tanning beds.

While you are undergoing treatment with azathioprine, and after you stop treatment with it, don't have any immunizations (vaccines) without your doctor's approval. Azathioprine may decrease your body's resistance and also the vaccine may well not are well or you may obtain the infection the vaccine is meant in order to avoid. In addition, you ought not be around other persons surviving in your household who receive live virus vaccines as there is an opportunity they might pass the herpes simplex virus on to you. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not get close to them and don't stay inside same room together for days on end. If you've got questions regarding this, talk to your physician.

Azathioprine can temporarily lower the number of white blood cells inside your blood, improving the possibility of getting contamination. It can also lower the quantity of platelets, that are essential for proper blood clotting. If this occurs, there are specific precautions you'll be able to take, particularly when your blood count is low, to reduce the probability of infection or bleeding:

Check with your physician without delay when you have several of the symptoms while you are employing this medicine: severe feeling sick; diarrhea; fever; rash; a general feeling of discomfort or illness; muscle or joint pain; lightheadedness or dizziness; or unusual tiredness or weakness. These could be symptoms of your serious reaction to the medicine inside your bowel (intestine).

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamins.

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