Keppra is employed to treat partial onset seizures in older adults and children who are a minimum of 1 month old.
It can also be used to take care of tonic-clonic seizures in grown-ups and children who're at least 6 years of age, and myoclonic seizures in adults and youngsters who are a minimum of 12 years old.
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Take Keppra exactly as prescribed by your doctor. Do not take in larger or smaller amounts and for over recommended. Follow the directions on your own prescription label.
Your doctor may occasionally alter your dose to ensure that you receive the best results.
Keppra is often taken twice daily. Take the medicine simultaneously daily. You may take Keppra with or without food.
Measure liquid medicine which has a special dose-measuring spoon or medicine cup, not using a regular table spoon. If you do not possess a dose-measuring device, ask your friendly phamacist first.
Do not crush, chew, or break a controlled release, delayed-release, or extended-release tablet. Swallow it whole. Breaking the pill might cause excessive drug to be sold in the past.
Use Keppra regularly to find the most benefit. Get your prescription refilled prior to deciding to run out of medication completely.
Do not stop using Keppra without first actually talking to your doctor, even if you feel fine. You could possibly have increased seizures if you stop employing this medicine suddenly. You might need to use less before you stop the medication completely.
Seizures tend to be treated using a combination of different drugs. Use all medications as directed through your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. .
Wear a medical alert tag or carry an ID card praoclaiming that you're taking Keppra. Any health care provider who treats you need to understand that you are taking seizure medication.
To be certain Keppra isn't causing harmful effects, your kidney function ought to be tested. Visit a medical expert regularly.
If you missed a dose - make missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to generate up the missed dose.
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Important Administration Instructions
Keppra emerges orally with or without food. The Keppra dosing regimen depends upon the indication, age bracket, dosage form (tablets or oral solution), and renal function.
Prescribe the oral solution for pediatric patients with body mass ≤ 20 kg. Prescribe the oral solution or tablets for pediatric patients with bodyweight above 20 kg.
When while using the oral solution in pediatric patients, dosing is weight-based (mg per kg) employing a calibrated measuring device (not only a household teaspoon or tablespoon).
Keppra tablets needs to be swallowed whole. Keppra tablets really should not be chewed or crushed.
Treatment should be initiated which has a daily dose of 14 mg/kg into two divided doses (7 mg/kg two tmes a day). The daily dose must be increased every 14 days by increments of 14 mg/kg for the recommended daily dose of 42 mg/kg (21 mg/kg twice a day). In the clinical study, the mean daily dose was 35 mg/kg in this age bracket. The effectiveness of lower doses has not been studied.
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Treatment must be initiated with a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg two tmes a day). The daily dose ought to be increased by 50 percent weeks by an increment of 20 mg/kg on the recommended daily dose of 50 mg/kg (25 mg/kg twice daily). If a patient cannot tolerate an everyday dose of 50 mg/kg, the daily dose may be reduced. In the clinical trial, the mean daily dose was 47 mg/kg with this population.
Treatment should be initiated using a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice a day). The daily dose ought to be increased every fourteen days by increments of 20 mg/kg on the recommended daily dose of 60 mg/kg (30 mg/kg twice a day). If a patient cannot tolerate a regular dose of 60 mg/kg, the daily dose might be reduced. In the clinical efficacy trial, the mean daily dose was 44 mg/kg. The maximum daily dose was 3000 mg/day.
For Keppra tablet dosing in pediatric patients weighing 20 to 40 kg, treatment must be initiated having a daily dose of 500 mg given as two tmes a day dosing (250 mg twice daily). The daily dose ought to be increased every 14 days by increments of 500 mg with a maximum recommended daily dose of 1500 mg (750 mg twice a day).
For Keppra tablet dosing in pediatric patients weighing over 40 kg, treatment must be initiated using a daily dose of 1000 mg/day given as twice a day dosing (500 mg twice daily). The daily dose must be increased every two weeks by increments of 1000 mg/day to some maximum recommended daily dose of 3000 mg (1500 mg two times a day).
Partial Onset Seizures
Adults 16 Years And Older
In many studies, daily doses of 1000 mg, 2000 mg, and 3000 mg, given as twice-daily dosing were been shown to be effective. Although in most studies there were a propensity toward greater response with higher dose [see Clinical Studies], an even surge in response with additional dose will not be shown.
Treatment ought to be initiated which has a daily dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Additional dosing increments may be given (1000 mg/day additional every two weeks) to some maximum recommended daily dose of 3000 mg. Doses higher than 3000 mg/day are actually utilized in open-label studies for periods of six months and longer. There is no evidence that doses more than 3000 mg/day confer additional benefit.
Myoclonic Seizures In Patients 12 Years of Age and Older With Juvenile Myoclonic Epilepsy
Treatment ought to be initiated using a dose of 1000 mg/day, given as twice-daily dosing (500 mg two tmes a day). Dosage should be increased by 1000 mg/day every two weeks towards the recommended daily dose of 3000 mg. The effectiveness of doses lower than 3000 mg/day is not studied.
Primary Generalized Tonic-Clonic Seizures
Adults 16 Years And Older
Treatment ought to be initiated using a dose of 1000 mg/day, given as twice-daily dosing (500 mg two times a day). Dosage should be increased by 1000 mg/day every fourteen days towards the recommended daily dose of 3000 mg. The effectiveness of doses under 3000 mg/day has not been adequately studied.
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Pediatric Patients Ages 6 To < 16 Years
Treatment ought to be initiated using a daily dose of 20 mg/kg in 2 divided doses (10 mg/kg twice a day). The daily dose must be increased every 14 days by increments of 20 mg/kg for the recommended daily dose of 60 mg/kg (30 mg/kg two tmes a day). The effectiveness of doses under 60 mg/kg/day has not been adequately studied. Patients with weight ≤ 20 kg should be dosed with oral solution. Patients with bodyweight above 20 kg can be dosed with either tablets or oral solution. Only whole tablets ought to be administered.
Adult Patients With Impaired Renal Function
Keppra dosing should be individualized according to the patient's renal function status.
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Store Keppra at room temperature faraway from moisture, heat, and light.
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Get emergency medical help should you have all of these warning signs of a hypersensitive reaction to Keppra: hives; difficult breathing; swelling of the face, lips, tongue, or throat.
Report any new or worsening symptoms to a medical expert, including: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your physician at once in case you possess a serious unwanted effect including:
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Less serious Keppra negative effects might include:
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This is just not a complete report on negative effects yet others may occur. Tell your doctor about any unusual or bothersome unwanted effect.
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You should not use Keppra should you are allergic to levetiracetam.
To ensure you can safely take Keppra, tell your doctor in the event you have kidney disease or high blood pressure.
You could have thoughts about suicide while using this medicine. Tell your physician if you have the signs of depression or suicidal thoughts in the first a few months of treatment, or when your dose is changed.
Your family and other caregivers should also be tuned in to changes with your mood or symptoms. Your doctor will likely need to check you at regular visits.
FDA pregnancy category C. It is not known whether Keppra will harm an unborn baby, but using a seizure while pregnant could harm both the mother and also the baby. Tell a medical expert in the event you are pregnant or prefer to get pregnant while employing this medication. Do not start or stop taking Keppra in pregnancy without your medical professional's advice. Seizure control is very important during pregnancy. The benefit of preventing seizures may outweigh any risks presented by taking Keppra. Follow your physician's instructions about taking Keppra when you are pregnant. Levetiracetam can pass into breast milk and might harm a nursing baby. You should not breast-feed while you are using Keppra. Do not give medicines to a child minus the advice of a doctor. Your child's dose needs are based on age and weight. The child should remain within the care of your doctor while using this medicine.
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Do not stop using Keppra without first speaking with your medical professional, in case you feel fine. You may have increased seizures in the event you stop using Keppra suddenly. You may need to use less prior to deciding to stop the medication completely.
You could have thoughts about suicide while taking Keppra. Your doctor will have to check you at regular visits. Do not miss any scheduled appointments.
Report any new or worsening symptoms to your physician, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Wear a medical alert tag or carry an ID card stating that you adopt Keppra. Any medical treatment provider who treats you have to know that you are taking seizure medication.
Keppra may impair your thinking or reactions. Be careful in case you drive or a single thing that will require you to definitely be alert. Tell a medical expert in the event you are pregnant or want to get pregnant while applying this medication. Do not start or stop taking Keppra during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm the two mother along with the baby. Seizure control is very important while pregnant along with the important things about preventing seizures may outweigh any risks resulting from using Keppra.
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Avoid drinking alcohol. It can increase many of the side effects of Keppra and could can also increase the risk of seizures. This medication may impair your opinions or reactions. Be careful if you drive or do anything whatsoever that will need one to be alert.
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