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NOOTROPIL is indicated for patients struggling with myoclonus of cortical origin, regardless of aetiology, and should be used in combination with other anti-myoclonic therapies.
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The dosage regime shows important interindividual variability, requiring an individualised dose finding approach. A reasonable protocol is always to introduce piracetam at the dosage of 7.2 g/day, increasing by 4.8 g/day every 3 to 4 days up to and including maximum of 20g/day, succumbed either a few divided doses while keeping other antimyoclonic drugs unchanged at their optimal dosage. If possible, depending on clinical benefit, an effort needs to be built to subsequently reduce the dosage of other antimyoclonic drugs.
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Store this medicine at room temperature in a tightly-closed container, away from heat and lightweight.
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The unwanted side effects reported regarding the Nootropil include nervousness, agitation, irritability, anxiety and sleep disturbances. The incidence of those during many studies was 5% or less plus they were more regularly noted inside the older patients taking more than 2.4 g daily. In the tastes cases a dose reduction sufficed to make these symptoms disappeared. Some patients may complain of fatigue or drowsiness. Gastro-intestinal problems for example nausea, vomiting, diarrhoea and stomachache are also reported, however their Incidence during numerous studies was 2% or less. Other symptoms, such as vertigo, headaches, trembling and sexual stimulation have occasionally been reported.
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NOOTROPIL (Piracetam) is contra-indicated in patients with severe renal impairment (renal creatinine clearance of below 20 ml for each minute), hepatic impairment and to those under 16 years of age. It is also contraindicated in patients with cerebral haemorrhage, Huntington's Chorea plus those with hypersensitivity to piracetam, other pyrrolidone derivatives or some of the excipients .
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Nootropil really should not be prescribed while pregnant or when breastfeeding.
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