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NOOTROPIL is indicated for patients struggling with myoclonus of cortical origin, inspite of aetiology, and should be used in conjunction with other anti-myoclonic therapies.

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The dosage regime shows important interindividual variability, requiring an individualised dose finding approach. A reasonable protocol should be to introduce piracetam at a dosage of 7.2 g/day, increasing by 4.8 g/day every three to four days up to a maximum of 20g/day, succumbed either a few divided doses while keeping other antimyoclonic drugs unchanged at their optimal dosage. If possible, based on clinical benefit, an effort needs to be designed to subsequently reduce the dosage of other antimyoclonic drugs.

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Store this medicine at room temperature in a very tightly-closed container, away from heat and light-weight.

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 Active ingredient: Piracetam

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Side Effects

The negative effects reported in association with Nootropil include nervousness, agitation, irritability, anxiety and sleep disturbances. The incidence of these during numerous studies was 5% or less and they also were more often noted in the older patients taking more than 2.4 g daily. In the tastes cases a dose reduction sufficed to generate these symptoms disappeared. Some patients may complain of fatigue or drowsiness. Gastro-intestinal problems such as nausea, vomiting, diarrhoea and stomachache have been reported, on the other hand Incidence during clinical trials was 2% or less. Other symptoms, for example vertigo, headaches, trembling and sexual stimulation have occasionally been reported.

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Precautions

NOOTROPIL (Piracetam) is contra-indicated in patients with severe renal impairment (renal creatinine clearance of lower than 20 ml for each minute), hepatic impairment and to those under 16 years. It is also contraindicated in patients with cerebral haemorrhage, Huntington's Chorea plus individuals with hypersensitivity to piracetam, other pyrrolidone derivatives or some of the excipients .

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Nootropil shouldn't be prescribed when pregnant or when breastfeeding.

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