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Prandin (repaglinide) is definitely an oral diabetes medicine that can help control blood glucose levels. This medication lowers blood glucose levels by inducing the pancreas to create insulin.

Prandin can be used together with dieting and exercise to help remedy diabetes. Other diabetes medicines are now and again used in combination with repaglinide if required.

Prandin may aso supply for purposes unlisted in this medication guide.


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Take Prandin just as prescribed through your doctor. Do not take in larger or smaller amounts and more than recommended. Follow the directions on the prescription label.

Prandin is usually taken 2 to 4 times daily, within 30 minutes before eating meals. Follow your doctor's instructions. If you skip lunch, do not take on your dose of Prandin. Wait until the next meal.

Your blood glucose should be checked often, and you may need other blood tests at your doctor's office. Visit your medical professional regularly.

Know signs and symptoms of low blood glucose levels (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.

Always keep a supply of sugar obtainable in case you might have signs and symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you've got severe hypoglycemia and can't eat or drink, make use of an injection of glucagon. Your doctor can provide a prescription for the glucagon emergency injection kit and show you the way to supply the injection.

Also look for indications of blood sugar that is excessive (hyperglycemia). These symptoms include increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dried-out skin, blurred vision, and fat loss.

Check your blood sugar levels carefully after a time of stress or illness, if you travel, exercise more than usual, are drinking alcoholic beverages, or skip meals. These things can impact your blood sugar levels plus your dose needs may also change.

Your doctor may want you to definitely stop taking Prandin for a small amount of time in case you become ill, use a fever or infection, or if you might have surgical procedures or a medical emergency.

Ask your medical professional how you can adjust your Prandin dose as required. Do not alter your medication dose or schedule without your medical professional's advice.

Prandin is just part of a complete program of treatment this includes diet, exercise, and weight loss. Follow your diet, medication, and employ routines very closely. Changing any of these factors can affect your blood sugar levels.

Use Prandin regularly to get the most benefit. Get your prescription refilled before you run out of medication completely.



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Active ingredient: Repaglinide

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Repaglinide is really a white to off-white powder with molecular formula C27 H36 N2 O4 and a molecular weight of 452.6. PRANDIN tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet provides the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and 2 mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.

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Side Effects

Weight gain, diarrhea, and joint may occur. If these effects persist or worsen, notify your physician or pharmacist promptly.

Remember that your physician has prescribed medicines as they or she's got judged that the advantage of you is in excess of the risk of negative effects. Many people using medicines will not have serious unwanted side effects.

Repaglinide can cause low blood glucose (hypoglycemia) especially if you are taking other medicines for diabetes. Consuming bulk of alcohol, to not get enough calories from food, or doing unusually heavy exercise could also bring about low blood glucose levels. Symptoms may include chills, cold sweat, dizziness, drowsiness, shaking, fast heartbeat, weakness, headache, fainting, tingling of the hands or feet, or hunger. It is a good habit to handle glucose tablets or gel to deal with low blood sugar. If you don't have these reliable kinds of glucose, lift up your blood sugar quickly when you eat a simple source of sugar such as white sugar, honey, candy, or drinking a glass of fruit juice or non-diet soda. Check with your medical professional or pharmacist to learn what you should do should you miss lunch.

Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your medical professional immediately. Your doctor should adjust your diabetes medication(s).

A serious allergic attack to this particular drug is rare. However, seek immediate medical attention should you notice any of the following signs and symptoms of a serious hypersensitive reaction: rash, itching/swelling (especially with the face/tongue/throat), severe dizziness, trouble breathing.

This is not a whole set of possible side effects. If you notice other effects unlisted above, contact your medical professional or pharmacist.


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Tell a medical expert about all the other medications you utilize, especially:

cyclosporine (Gengraf, Neoral, Sandimmune);

St. John's wort;

an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), or telithromycin (Ketek);

an antifungal medication including fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Nizoral);

a barbiturate such as phenobarbital (Solfoton);

heart or blood pressure medication such as diltiazem (Cartia, Cardizem), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), while others;

HIV/AIDS medicine such as delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), fosamprenavir (Lexiva), indinavir (Crixivan), ritonavir (Norvir), and others;

rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin); or

seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), primidone (Mysoline), yet others.

You might be prone to have hyperglycemia (high blood glucose levels) in case you consider Prandin with drugs that raise blood glucose, like:


diuretics (water pills);

steroids (prednisone among others);

phenothiazines (Compazine yet others);

thyroid medicine (Synthroid while others);

birth control pills along with other hormones;

seizure medicines (Dilantin yet others); and

diet pills or medicines to deal with asthma, colds or allergies.

You could possibly be more likely to have hypoglycemia (low blood glucose) in the event you take other drugs that lower blood glucose, such as:

probenecid (Benemid);

a blood thinner (warfarin, Coumadin);

some nonsteroidal anti-inflammatory drugs (NSAIDs);

aspirin or another salicylates (including Pepto-Bismol);

a blood thinner (warfarin, Coumadin, Jantoven, yet others);

sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, while others);

a monoamine oxidase inhibitor (MAOI); or

other oral diabetes medications, especially acarbose (Precose), metformin (Glucophage), miglitol (Glyset), pioglitazone (Actos, Duetact, Actoplus Met), or rosiglitazone (Avandia, Avandaryl, Avandamet).

These lists are certainly not complete where there are lots of other medicines that will increase or decrease the effects of Prandin on cutting your blood glucose levels. Using certain medicines can make it harder for one to tell when you've low blood sugar. Tell your medical professional about all medications you employ. This includes prescription, over-the-counter, vitamin, and herbal products. Do not find a new medication without telling your medical professional.


Do not use Prandin if you are allergic to repaglinide, if you might have type 1 diabetes, or should you are in a state of diabetic ketoacidosis (call your physician for treatment with insulin). You should not use Prandin along with gemfibrozil (Lopid) or NPH insulin (including isophane insulin).

Before taking repaglinide, tell your doctor or pharmacist in case you are allergic to it; or if you have every other allergies. This product could have inactive ingredients, which could cause allergy symptoms or any other problems. Talk to your pharmacist for additional information. 

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease.

You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or inflict activity that requires alertness or clear vision unless you are sure you'll be able to perform such activities safely.

Limit alcohol while taking this medication given it can increase potential risk of developing low blood glucose levels.

During times during the stress, like fever, infection, injury, or surgery, it could be tougher to regulate your blood sugar levels. Consult your physician because increased stress may require a modification of your treatment plan, medications, or blood sugar levels testing.

During pregnancy medicines should be utilized only when clearly needed. Pregnancy could cause or worsen diabetes. Discuss an agenda with your medical professional for managing your blood glucose while pregnant. Your doctor may make positive changes to diabetes treatment during your pregnancy. Discuss the potential for loss and great things about different treatments (including diet, exercise, and medications including insulin).

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FDA pregnancy category C. It is not known whether Prandin will harm an baby. Tell your physician if you are pregnant or plan to become pregnant with all the Prandin. It is not known whether repaglinide passes into breast milk or if it can be bad for a nursing baby. You should not breast-feed while you are taking Prandin.

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