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Promethazine is within a gaggle of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing those things of chemicals within your brain. Promethazine also acts as a possible antihistamine. It blocks the effects in the naturally sourced chemical histamine inside your body.

Promethazine is employed to treat allergic reactions for example itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Promethazine also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid.

Promethazine just isn't for use for treating signs of asthma, pneumonia, or other lower respiratory tract infections.

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Take promethazine just as prescribed from your doctor. Do not take it in larger amounts and more than recommended. Follow the directions in your prescription label.

Your doctor may occasionally improve your dose to ensure that you receive the best comes from this medication.

Promethazine might be taken with or without food or milk.

Measure liquid medicine having a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a very dose-measuring device, ask the pharmacist first.

Call your doctor should your symptoms don't improve, or if they worsen while taking promethazine.

This medication might cause you to have unusual results with certain lab tests. Tell any doctor who treats you that you are using promethazine.

Seek emergency medical assistance if you think maybe you've used too much of this medicine. Overdose symptoms might include severe drowsiness, dizziness, dry mouth, large pupils, flushing, nausea, vomiting, shallow breathing, and fainting.

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Take it as being prescribed through your doctor.

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Store promethazine at room temperature away from moisture, heat, and light.

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Side Effects

Get emergency medical help if you've all of these warning signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using promethazine and call your doctor simultaneously if you have these serious negative effects:

twitching, or uncontrollable movements of one's eyes, lips, tongue, face, arms, or legs;

tremor (uncontrolled shaking), drooling, trouble swallowing, difficulty with balance or walking;

feeling restless, jittery, or agitated;

high fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, rapid breathing;

feeling like you might distribute;

seizure (convulsions);

pale skin, easy bruising or bleeding, fever, sore throat, flu symptoms;

decreased night vision, tunnel vision, watery eyes, increased sensitivity to light;

hallucinations, agitation;

nausea and stomach pain, skin rash, and jaundice (yellowing from the skin or eyes);

urinating below usual or not at all;

joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color; or

slow pulse rate, weak pulse, fainting, slow breathing (breathing may stop).

Less serious promethazine unwanted effects can include:

dizziness, drowsiness, anxiety;

blurred vision, dry mouth, stuffy nose;

ringing with your ears;

weight gain, swelling within your hands or feet;

impotence, trouble using an orgasm; or


This just isn't a complete listing of negative effects and others may occur. Tell a medical expert about any unusual or bothersome side effect.

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Stop using promethazine and call your doctor immediately if you might have twitching or uncontrollable movements of your respective eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous unwanted effects. Promethazine can cause unwanted side effects that could impair your notions or reactions. Be careful in the event you drive or a single thing that needs you to definitely be awake and alert. Avoid alcohol consumption, which may increase some with the unwanted effects of promethazine. There are many other medicines that could connect to promethazine. Tell a medical expert about all the prescription and over-the-counter medications you utilize. This includes vitamins, minerals, herbal products, and prescription drugs given by other doctors. Do not employ a new medication without telling your doctor. Keep a list together with you of all of the medicines you utilize and show this list to the doctor or any other healthcare provider who treats you.

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Important safety information:

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Promethazine really should not be provided to a young child younger than 2 years old. Promethazine may cause severe breathing problems or death in a kid younger than 2. Carefully follow your physician's instructions when giving this medicine to a young child of any age. Do not use prescription drugs if you have severe asthma, emphysema, and other breathing problem, or if you are allergic to promethazine and other phenothiazines including chlorpromazine (Thorazine), fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), thioridazine (Mellaril), or trifluoperazine (Stelazine).

If you've certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take promethazine, tell your medical professional if you've got:

a good reputation for seizures;

heart disease or high blood pressure levels;

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liver or kidney disease;

severe asthma, emphysema, chronic obstructive pulmonary disease (COPD) or any other breathing problem;

sleep apnea (breathing stops during sleep);


a stomach ulcer or digestive obstruction;

bone marrow depression;

adrenal gland tumor (pheochromocytoma);

enlarged prostate or difficulties with urination;

low numbers of calcium in your blood (hypocalcemia); or

if you have ever a serious complication while using the promethazine or another phenothiazine.

FDA pregnancy category C. It isn't known whether promethazine is harmful to a developing fetus. Tell a medical expert if you are pregnant or want to become pregnant during treatment. It is not known whether promethazine passes into breast milk or if it might harm a nursing baby. Do not use medicines without telling your physician in the event you are breast-feeding an infant. Older adults may be very likely to have unwanted side effects from promethazine.

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