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Tofranil (Imipramine) is within a small grouping of drugs called tricyclic antidepressants. Imipramine affects chemicals in the brain that could become unbalanced.
It is used to treat the signs of depression.
This medicine may also be used for purposes apart from those classified by prescription drugs guide.


Take this medication the same manner it turned out prescribed to suit your needs. Do not take the medication in larger amounts, or go more than recommended because of your doctor. Your doctor may occasionally change your dose to ensure that you receive the best is a result of medicines. Follow the directions on your own prescription label.
If you'll want almost any surgery, tell the surgeon in advance that you're taking imipramine. You may need to stop while using the medicine for the small amount of time.
Do not stop using imipramine without first actually talking to your medical professional. You may need to use much less before you decide to stop the medication completely. Stopping prescription drugs suddenly could cause that you have unpleasant unwanted effects. It may take up to 25 days of employing this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your physician if the symptoms don't improve after 3 weeks of treatment.

If you missed the dose go when you remember. If it's almost time for your forthcoming dose, skip the missed dose and consider the medicine at the next regularly scheduled time. Do not take extra medicine to produce inside the missed dose.

Seek emergency medical assistance if you believe you might have used an excessive amount of this medicine. An overdose of imipramine could be fatal.
Symptoms associated with an imipramine overdose can sometimes include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, sweating, muscle stiffness, swelling, difficulty breathing, blue lips or fingernails, feeling light-headed, fainting, seizure (convulsions), or coma.


Take this medicine as prescribed by your doctor.


Store imipramine at room temperature from moisture as well as heat.


Active Ingredient: Imipramine

Tofranil is a tricyclic antidepressant. It works by helping the activity of certain chemicals in the brain that help elevate mood.

Side Effects

Get emergency medical help if you've some of these signs of your allergic reaction: hives; lack of breath; swelling of your face, lips, tongue, or throat.

Call your doctor at the same time if you've any new or worsening symptoms like: mood or behavior changes, anxiety, anxiety attacks, sleep disorders, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call a medical expert simultaneously if you've all of these serious unwanted effects:

fast, pounding, or uneven heart rate;

chest pain or heavy feeling, pain spreading for the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness or weakness, especially on one side of the body;

sudden headache, confusion, problems with vision, speech, or balance;

feeling in short supply of breath, despite mild exertion;

swelling, rapid putting on weight;

confusion, hallucinations, or seizure (convulsions);

easy bruising or bleeding, unusual weakness;

restless muscle movements within your eyes, tongue, jaw, or neck;

urinating more or less than usual;

extreme thirst with headache, nausea, vomiting, and weakness;

skin rash, bruising, severe tingling, numbness, pain, or muscle weakness.

Less serious unwanted side effects could possibly be more prone to occur, such as:

nausea, vomiting, stomach pain, loss in appetite;

constipation or diarrhea;

dry mouth, unpleasant taste;

weight changes;

weakness, lack of coordination;

feeling dizzy, drowsy, or tired;


blurred vision, headache, ringing inside your ears;

breast swelling (in men or women); or

decreased sexual libido, impotence, or difficulty using an orgasm.

Tofranil will be used only through the patient for whom it really is prescribed. Do not share it with other people.
If your symptoms don't improve or if they become worse, consult a medical expert.


Do not use Tofranil if:

you might be allergic to your ingredient in Tofranil;

you have taken furazolidone or possibly a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) during the last fourteen days, or if you adopt astemizole, droperidol, or terfenadine.

you are coping with a recent heart attack.
Contact your doctor or health care provider right away if some of these affect you.

Some medical conditions may connect to Tofranil . Tell your physician or pharmacist if you've got any health conditions, in particular when any in the following affect you:

if you might be pregnant, likely to become pregnant, or are breast-feeding

if you're taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you might have allergies to medicines, foods, and other substances

if you drink alcohol-containing beverages daily or you have a good alcohol abuse

if you take thyroid medicine or you've got a good overactive thyroid, glaucoma, heart disease, kidney or liver problems, diabetes, seizures, the blood disease porphyria, or difficulty urinating

if you've got a history of suicidal thoughts or behavior, bipolar disorder, or some other mental disorders; you might be undergoing electroshock therapy; or you might be scheduled to own any surgery.

Some MEDICINES MAY INTERACT with Tofranil . Tell your physician if you are taking every other medicines, especially any in the following:

Azole antifungals (eg, fluconazole), cimetidine, duloxetine, flecainide, methylphenidate, mibefradil, phenothiazines (eg, chlorpromazine), propafenone, quinidine, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or terbinafine since they could raise the probability of Tofranil 's unwanted side effects

Arsenic, astemizole, droperidol, furazolidone, MAOIs (eg, phenelzine), pimozide, streptogramins (eg, dalfopristin), terfenadine, or tramadol since the likelihood of high blood pressure, serious heart disease (eg, irregular heartbeat), or seizures could be increased

Barbiturates (eg, phenobarbital) or phenytoin since they may decrease Tofranil 's effectiveness

Anticholinergics (eg, benztropine), carbamazepine, or sympathomimetics (eg, phenylephrine) because the likelihood of their negative effects might be increased by Tofranil

Clonidine, guanethidine, or guanfacine because their effectiveness might be decreased by Tofranil

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